Will need to know a few things:
What fuel do you plan to run?
What crank and piston combination?
Are you having it built or building it yourself?
Are you planning to have it cleaned up, fully ported or running as cast?
Most common base gaskets for a 421 are a .012 and a .020, selection is really builder preference. As for you question on the domes, 17cc is way too small. Dome size is really up to the builder as well. We typically use 21cc domes for 110 octane. The domes have to be sized for a 68mm bore or they will NOT work. Your absolute best bet is to contact a reputable builder and have them help you get the right parts.
-Brandon